The development of allergy in relation to age can be described as an "allergy march". This means that there is often a given direction, once atopic immune responses associated with IgE antibodies have been initiated and induced the atopic state. The manifestation of atopic disease varies considerably with the age of the child, as do the allergens involved. In infancy allergies to foods seem to be the most common, after the age of 3 allergy to inhalant becomes predominant. New causative allergens could be added due to higher concentrations of exposure, or as quite new allergens. However, the immune system tends to be less active in older days (1).