Is it possible to obtain positive specific IgE results if total IgE is within the normal range?

ImmunoCAP Total IgE

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The normal range for ImmunoCAP Total IgE generally used for adults is <100kU/l. A positive result for a specific allergen is defined as >/= 0.35 kUA/l.
 
The different concentration levels of specific IgE compared with total IgE consequently make it possible to obtain values below 100 kU/l for total IgE, and several positive specific IgE results for a patient. For further information about ImmunoCAP assays for detection of atopic patients, please refer to the Knowledge base document Phadiatop, design and performance.
 
References
  1. Liappis, N; Berdel, B. Determination of total IgE and of specific IgE in the serum of capillary blood. Allergologie;1998;11:10-12.
  2. Lilja, G; Magnusson C G; et al. Neonatal IgE levels and three different blood sampling techniques. Allergy;1992;47:522-526.
  3. Bauer, C; Atopy screening in children: Total IgE, Phadiatop, and RAST multiple food allergen disc performed on capillary blood samples. Allergologia e Immunologia Clinica; 1987; 2:95.