Expected Values

The level of specific IgG antibodies in healthy persons to different antigens may vary considerably due to different exposure. To determine if levels are increased, the reference level of specific IgG antibodies to a certain antigen must be measured in a number of samples from normal healthy persons and, if possible, compared with the levels in a disease group of patients. There is no common cut-off value for specific IgG antibodies, as these are markers for antigen exposure and are not directly related to the disease. Results vary both within and between antigens.