Expected Values

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A positive Phadiatop result demonstrates the presence of an atopic constitution.
 
The physician can then proceed with more specific testing to confirm the causative allergen.

A negative result indicate no atopy, i.e. the symptoms are not caused by common environmental allergens. If a suspicion of IgE-mediated allergy remains the physician can then explore other possibilities (allergens).
 
ImmunoCAP Phadiatop can be expressed in semiquantitative or qualitative results. For Phadiatop with a semiquantitative evaluation, the response is evaluated against the Specific IgE calibration curve and expressed in PAU/l (Phadia Arbitrary Units/l). PAU is defined as an arbitrary unit of specific IgE antibodies, not equivalent to kUA of specific IgE. For Phadiatop with a qualitative evaluation, Phadiatop results are expressed as positive or negative, in clinical practice the 0.35 kU/l Specific IgE calibrator has commonly been used as a cut-off, however, the user is free to establish any suitable cut-off above the limit of quantitation.

Interpretation of results

Semiquantitative results
Phadiatop results are expressed as Phadia Arbitrary Units/l (PAU/l) indicating degree of sensitization. A Phadiatop PAU/l value above limit of quantitation indicates that the patient is atopic (positive), i.e. measurable levels of specific IgE antibodies to common inhalant allergens have been detected.

A Phadiatop PAU/l value below limit of quantitation indicates that the patient is non-atopic (negative), i.e. the level of specific IgE antibodies is undetectable.

Higher Phadiatop PAU/l values indicates higher degree of sensitization i.e. higher levels of specific IgE antibodies to common inhalant allergens.
 
Qualitative results
Phadiatop results are expressed as positive or negative.

A positive Phadiatop result indicates that the patient is atopic, a negative result indicates that the patient is non-atopic, i.e. not sensitized to inhalant allergens.

In order to determine the concentration of allergen specific IgE antibodies, it is recommended to retest the sample with the appropriate ImmunoCAP Specific IgE allergens.